Confirmation of diagnosis

Prior treatment

Confirmation of recurrence

Confirmation of response to ANP

Tumor measurements

Pathology

Radiology

Patient

Place and date

Diagnosis

Place and date

Diagnosis

Date

Assessment

Place and date

Assessment

MRI

PET

Enhancing

Non-enhancing

1

AMCMarch 10, 1995 February 26, 1999

A GS

AMCMarch 24, 1999

DIPG

2S 3RT 2C HDC

December 3, 1999

Recurrent tumor, DIPG and multicentric

External radiology, CRR, April 12, 2000

CR

Decreased over 50%

Decreased

Resolved

2

AMCAugust 9, 1999

DIPG

RT

November 3, 1999

Recurrent tumor

External radiology, CRR February 23, 2000

PR

Decreased over 50%

Decreased

3

AMCJanuary 4, 1999

DIPG

RT C

April 27, 1999

Recurrent tumor

External radiology, CRR June 18, 1999

PR

Decreased over 50%

Decreased

4

AMCApril 11, 2011

DIPG

RT C Targeted (bevacizumab)

October 20, 2011

Recurrent tumor

External radiology, July 30, 2012

PR

Decreased over 50%

Decreased

5

RGDecember 3, 1995

DIPG

RT

February 21, 1996

Recurrent tumor

External radiology, May 22, 1996

SD

Stable

Stable

6

AMCJuly 31, 1998

DIPG

RT

October 26, 1998

Recurrent tumor

External radiology, March 18, 1999

SD

Stable

Stable

7

AMCMarch 30, 2005

A2

RGMarch 10, 2005

DIPG

C

May 24, 2005

Recurrent tumor

External radiology, September 12, 2005

SD

Stable

Stable

8

RGMarch 1, 2010

DIPG

RT C

July 27, 2010

Persistent tumor

RGMay 26, 2011

SD

Stable

Stable

9

AMCAugust 24, 1999

AA

AMCAugust 20, 1999

Right thalamic tumor

RT

October 27, 1999

Recurrent tumor

External radiology, CRR, April 12, 2000

PR

Decreased over 50%

Stable

10

AMCDecember 24, 1998

AA

AMCDecember 19, 1997

Left temporal tumor

2S RT 4C

September 23, 1999

Recurrent tumor

External radiologyJune 18, 2000

SD

Stable

Stable

11

AMCMay 19, 2003

GBM

AMCMay 12, 2003

Left temporal tumor

S RT C

August 20, 2003

Recurrent tumor

External radiology, December 4, 2003

SD

Stable

Decreased

12

AMCMay 8, 2009

GBM

AMCJune 2, 2009

Right temporal tumor

2S RT 2C

October 14, 2009

Recurrent tumor

External radiology, February 8, 2010

SD

Stable

Stable